Overview · Thursday, Apr 30
0 findings synthesized across labs, wearables, and genetics.
Last sync · Today, 06:42
⬤ All sources connected
Bio-age 0.0 · Chrono 27
Today's read
Iron status is the dominant signal this week. HRV trend tracks ferritin, not training load. Worth a follow-up panel before the next quarterly check-in.
Vitals · last 14 days
Cross-domain signals worth surfacing this week.
wearable × lab
Resting HRV is down 11% over 90 days. It lines up almost perfectly with the ferritin trend on your last iron panel. Iron deficiency throttles autonomic recovery before it ever shows up as low hemoglobin. Worth a recheck and possibly a short ferrous-sulfate trial.
nutrition
Latest 25-OH vitamin D is 24 ng/mL — outside the deficient range, but below the 30 ng/mL threshold most clinicians use. Consider 4,000 IU/day through winter and re-test in 8–12 weeks.
lab trend
TSH has climbed from 1.6 → 4.5 mIU/L across the last four panels. You're still inside the lab's reference range, but the trajectory matters. Subclinical hypothyroidism can present this way years before it becomes overt.
drug × gene
Your CYP2C19 genotype means your body breaks down clopidogrel (Plavix) more slowly than average. You don't take it today — but if any cardiologist ever prescribes it, ask about prasugrel or ticagrelor instead.
lifestyle × gene
Your CYP1A2 genotype suggests slow caffeine clearance. With your usual ~3pm latte, half the dose is still in your system at sleep onset — which lines up with the REM fragmentation we're seeing on Oura.
wearable
Strain rose to 12.4 over the last week (about 18% over your baseline) while recovery has held at 72%. You're still inside the green, but a deload week could buy back HRV and protect against an upper-respiratory dip.
Bayesian state
Each carries evidence, a rationale, and a validation path.
Declining ferritin (90d) → reduced O₂ delivery → HRV suppression and rising RHR. Validate with CBC + reticulocytes; consider 100mg ferrous sulfate trial.
TSH trending up across last 4 draws while free T4 holds within range. Below threshold for clinical action; re-check at next panel.
Total sleep duration steady at 7h 12m. REM fragmentation increasing. Subjective fatigue correlates with REM minutes more than total minutes.
Last 30 days
Iron panel · drawn
17d agoQuest · Ferritin 14 ng/mL flagged low
Thyroid trend
17d agoQuest · TSH 4.5 mIU/L ↑ 22% across last 4 panels
PGS recompute
3d agoFurther engine · 7 traits · EUR cohort, all green calibration
HRV reading
TodayWHOOP · 58 ms · 14% below 90-day baseline
Sleep score
TodayOura · 72 / 100 · REM fragmentation up