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Medications

Prescriptions × pharmacogenomics.

Your active meds and supplements, cross-referenced against your CYP450 profile. Findings are written in plain English first; medical detail is one click away.

Active

3 prescriptions and supplements.

    Vitamin D3

    2000 IU · Daily · RxCUI 315960

    active

    Omega-3 (EPA/DHA)

    1000 mg · Daily · RxCUI 9333

    active

    Magnesium glycinate

    300 mg · Evening · RxCUI 29155

    active

Pharmacogenomics · CPIC-graded

How your DNA changes how meds work.

Plain English first. Medical terminology and CPIC dosing in the expandable section.

  • CYP2C19 · Level A

    Poor metabolizer (*2/*2)

    Action when prescribed

    What this means

    Some heart and antidepressant meds work differently for you.

    Your body breaks down a small group of common drugs slowly. The biggest one to know is clopidogrel (brand name Plavix), an antiplatelet often prescribed after a heart event. For people like you, it doesn't get fully activated and can leave a heart at higher risk than expected. If a cardiologist ever proposes it, ask about prasugrel or ticagrelor instead. Some SSRIs (citalopram, escitalopram) and the antifungal voriconazole also need lower doses for you.

    Drugs affected

    ClopidogrelVoriconazoleCitalopramEscitalopram
    Medical detailFor your records

    Phenotype

    CYP2C19 *2/*2 phenotype with reduced enzymatic activity (1–15% of extensive metabolizer baseline). Affects activation of clopidogrel and clearance of CYP2C19 substrates.

    CPIC guidance

    CPIC guideline (2022 update) recommends prasugrel or ticagrelor as the antiplatelet of choice for CYP2C19 poor metabolizers requiring P2Y12 inhibition. For citalopram/escitalopram, start at 50% of standard dose.

  • CYP2D6 · Level A

    Normal metabolizer

    Informational

    What this means

    You process pain meds and tamoxifen the standard way.

    No surprises here. Codeine and tramadol will give you the expected pain relief at normal doses. Tamoxifen (used in breast-cancer treatment) will be activated normally too. Nothing to flag.

    Drugs affected

    CodeineTramadolTamoxifen
    Medical detailFor your records

    Phenotype

    CYP2D6 normal metabolizer phenotype. Standard dosing applies for all CYP2D6 substrates.

    CPIC guidance

    CPIC guideline: standard dosing for opioids (codeine, tramadol) and tamoxifen.

  • CYP1A2 · Lifestyle

    Slow metabolizer

    Informational

    What this means

    Caffeine sticks around in your system longer than most people's.

    Most people clear half their caffeine in about 5 hours. For you it's closer to 8–9. That afternoon coffee is still on board at bedtime, which fits the REM fragmentation we're seeing on your wearable. Try moving your last caffeine of the day before 2pm and re-evaluate sleep in two weeks.

    Drugs affected

    CaffeineTheophyllineOlanzapine
    Medical detailFor your records

    Phenotype

    CYP1A2 *1F/*1F or similar slow-inducer haplotype. Reduced caffeine and theophylline clearance.

    CPIC guidance

    No formal CPIC dosing guideline; lifestyle adjustment recommended for caffeine timing.

  • MTHFR · Level B

    C677T heterozygous

    Informational

    What this means

    You have a small folate-processing variant — usually no action needed.

    MTHFR variants are common — about 1 in 3 people carry one copy like you. It mildly reduces how your body processes folate, but real-world impact for healthy people is small. Standard prenatal doses are fine. The variant only becomes clinically relevant for very high methotrexate doses.

    Drugs affected

    MethotrexateFolate metabolism
    Medical detailFor your records

    Phenotype

    MTHFR C677T heterozygous (CT). Approximately 65% enzymatic activity vs CC genotype. Population frequency ~30–40%.

    CPIC guidance

    No general dose adjustment recommended. Considered for high-dose methotrexate regimens only.