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Medications

Prescriptions × pharmacogenomics.

Your active meds and supplements, cross-referenced against your CYP450 profile. Findings are written in plain English first; medical detail is one click away.

Active

3 prescriptions and supplements.

    Vitamin D3

    2000 IU · Daily · RxCUI 315960

    active

    Omega-3 (EPA/DHA)

    1000 mg · Daily · RxCUI 9333

    active

    Magnesium glycinate

    300 mg · Evening · RxCUI 29155

    active

Pharmacogenomics · CPIC-graded

How your DNA changes how meds work.

Plain English first. Medical terminology and CPIC guideline detail in the expandable section.

  • CYP2C19 · Level A

    Poor metabolizer (*2/*2)

    Share with your prescriber

    What this means

    Some heart and antidepressant medicines may work differently for you.

    Your body breaks down a small group of common medicines slowly. The best known is clopidogrel (Plavix), an antiplatelet medicine. With your result, it may not be fully activated in your body. This enzyme also processes some SSRIs, such as citalopram and escitalopram, and the antifungal voriconazole. Share this result with any clinician who prescribes for you.

    Drugs affected

    ClopidogrelVoriconazoleCitalopramEscitalopram
    Medical detailFor your records

    Phenotype

    CYP2C19 *2/*2 phenotype with reduced enzymatic activity (1–15% of extensive metabolizer baseline). Affects activation of clopidogrel and clearance of CYP2C19 substrates.

    CPIC guidance

    CPIC Level A guideline (2022 update) covers CYP2C19 with clopidogrel, citalopram, escitalopram, and voriconazole. A prescriber can review it alongside this result.

  • CYP2D6 · Level A

    Normal metabolizer

    Informational

    What this means

    You process pain meds and tamoxifen the standard way.

    No surprises here. Your result is the most common one. Codeine, tramadol, and tamoxifen are processed by this enzyme the way they are for most people. Nothing unusual to flag.

    Drugs affected

    CodeineTramadolTamoxifen
    Medical detailFor your records

    Phenotype

    CYP2D6 normal metabolizer phenotype. No variant alleles called.

    CPIC guidance

    CPIC guidelines cover CYP2D6 with codeine, tramadol, and tamoxifen. Normal metabolizers are the reference group in those guidelines.

  • CYP1A2 · Lifestyle

    Slow metabolizer

    Informational

    What this means

    Caffeine sticks around in your system longer than most people's.

    Most people clear half their caffeine in about 5 hours. For you it's closer to 8–9. An afternoon coffee may still be active at bedtime, which fits the REM fragmentation on your wearable. Your caffeine timing and your sleep data are worth watching side by side.

    Drugs affected

    CaffeineTheophyllineOlanzapine
    Medical detailFor your records

    Phenotype

    CYP1A2 *1F/*1F or similar slow-inducer haplotype. Reduced caffeine and theophylline clearance.

    CPIC guidance

    No formal CPIC guideline for CYP1A2. The caffeine link comes from metabolism research, not a clinical guideline.

  • MTHFR · Level B

    C677T heterozygous

    Informational

    What this means

    You have a small folate-processing variant — usually no action needed.

    MTHFR variants are common. About 1 in 3 people carry one copy, like you. It mildly reduces how your body processes folate, and the real-world impact for healthy people is small. It comes up mostly in research on methotrexate.

    Drugs affected

    MethotrexateFolate metabolism
    Medical detailFor your records

    Phenotype

    MTHFR C677T heterozygous (CT). Approximately 65% enzymatic activity vs CC genotype. Population frequency ~30–40%.

    CPIC guidance

    No CPIC guideline applies to this result for most medicines. It is mainly discussed in methotrexate research.